One of the founding members of Overwatch, Ana uses her skills and expertise to defend her home and the people she cares for.

As the Omnic Crisis inflicted a heavy toll on Egypt, the country's depleted and undermanned security forces relied on elite snipers for support. Among them was Ana Amari, who was widely considered to be the world's best. Her superior marksmanship, decision-making, and instincts made her a natural selection to join the Overwatch strike team that would end the war.