Anne-Sophie de Grantaine is Tamaki Suoh's mother. She lives in France and mothered Tamaki with Yuzuru Suoh, her lover and eventual husband.

She meets Yuzuru Suoh in Paris while he's on a business trip. The two fall in love and she becomes his mistress. When Tamaki is born, she is forbidden by Yuzuru's mother, Shizue Suoh, to return to Japan with Yuzuru. She remains in France, raising René aka Tamaki, until he is fourteen. As Tamaki grows up, Anne-Sophie's health steadily declines.

When the de Grantaine family business goes into debt and is near bankruptcy, Shizue Suoh offers a deal to Anne-Sophie. In exchange for financial security and medical care until the end of her days, she is to relinquish all control and visitation of Tamaki to herself. Shizue does this because she is concerned for the Suoh legacy, Yuzuru having no other children to whom he can pass on the family and business legacies. Anne-Sophie tearfully accepts and it is said that she leaves France and goes into seclusion following Tamaki's departure.