Tsuyu is a straightforward and quite laid-back girl who always says what's on her mind and what she thinks about others. She prefers to be called by her given name, but has stated she only wants people she views as friends to refer to her as such.[1] She has proven to be very observant, as she was the first to note the similarities between Izuku and All Might's Quirks.

Tsuyu is also noticeably calm and collected, being able to stay level headed in stressful situations. Recovery Girl describes her as the "perfect pillar of emotional support".[2] Her usual expression consists of a vacant stare, which makes reading her thoughts and emotions difficult for those around her.

Tsuyu has a habit of tipping her finger against her mouth while speaking or pondering.