Henry Fisher was the father of Sal Fisher, the husband of the late Diane Fisher, and husband to Lisa Johnson following his first wife's death.

Henry was a devoted and hardworking father who was committed to his job to make ends meet. He was a loving husband to his first wife, Diane, and missed her dearly; despite Sal's belief that he had gotten rid of all photos of her, Sal later finds one under his bed alongside a letter from her. He had also made his computer password her name.

Her death had a deeply terrible impact on his life, sending him into a depressive state that lead to a dependency on alcohol. His resulting mercurial temperament put a strain on his relationship with Sal. Henry then lost his job, allowing himself and Sal to move from New Jersey to Nockfell.

After moving to Addison Apartments, Henry's mental health slowly improved, notably in part due to Lisa Johnson. After courting her and marrying her, Henry seemed to be once again content with where his life was.