Yuri is portrayed throughout the majority of the game as being shy, generous, polite, apologetic, very intelligent, mature, eloquent, and passionate about topics she is interested in, although she is also very insecure, awkward, and has a tendency to act slightly condescending and patronizing to mask her self-doubt. Her façade of passivity and level-headed nature occasionally breaks, however, as Yuri does argue passionately and aggressively with Natsuki over their differing opinions on writing styles and types of literature. Yuri has a deep desire to be liked by others and is afraid to speak her mind on certain matters as she believes it will make her seem unlikable. Due to her social ineptitude, she can be innocently insensitive, but once she realizes what she said could be considered rude, she almost immediately apologizes, repeatedly saying she did not mean it. As stated by the protagonist, Yuri likes to think before she says something. (Description pulled from the fandom wiki).

Yuri should have a low to mid pitch and mature tone.  Yuri is shy, and should speak softly. Do not make her voice so soft that she cannot be heard in your audition.  Amplify is a good tool to use if you find your audition needs a little boost. She doesn’t speak to others often, and she should not sound comfortable talking to others.