CONTEXT: Regina is defeated. After trying to defeat Batman by sending Gotham's worst after him, she realizes that she isn't the one to do it. This scene takes place after a failing fight between the two, Regina his bruised, and hurt, yet she doesn't even feel anything.

"REGINA: 

(emotionless, getting drenched in rain)

Every punch, every kick, every cut... I thought you would be the one. I watched you throughout all of the chaos, and I thought you would be the one-... 

(IN A FIT OF RAGE, leaning into a yell) 

Who would make me FEEL SOMETHING! 

(pause)

But you aren't... The doctors all said the same thing. I'm just void of it. Emotion. I can never feel love, anger, sadness... I have blood coming down my nose, and while I can taste the iron, I can't feel the sting..."

In this scene, she's defeated. She is upset because she's a diagnosed sociopath. She also has a rare condition in her muscle tissue called Congenital insensitivity to pain and anhydrosis (CIPA).

She's angry at the world for not only leaving her void of emotion, but void of pain. 

Voice type: From the Director's words, he'd like an actress who can go both high pitched and low pitched in range.