Nejire is naturally a very kind, talkative and endlessly curious girl. She shows great interest in people's unique physical features and is easily distracted by them. Due to this, Nejire can be very blunt, often asking rather invasive or off-putting questions.

Nejire is an affectionate person and a "free spirit," someone who has a genuine passion for learning new and strange things and isn't afraid to speak her mind or show how she feels. She seems to like knowing more than others, but not in a proud way, as she just enjoys explaining things to people and sharing her knowledge. She is mentioned to act like a kindergartner due to her childish glee.

She is very enthusiastic, affable and cheery, and is always seen moving. She does not seem very concerned for Tamaki Amajiki when she learns of his attack, possibly due to having a more optimistic view than everyone else. Thanks to her inquisitive and chatty demeanor, she is a notably level-headed individual, though she comes off as an "airhead" most of the time.

Despite her happy go lucky personality, Nejire is fierce in battle. When the situation calls for it, Nejire can be very calm and focused. Her curiosity never seems to extend to the enemy and she always maintains her focus on taking them down. Her strong heart is what has allowed her to climb the ranks into one of U.A.'s top three students.