Rose is a patient at the Berthow Women's Psychiatric Hospital, and also a main charater in Insane.

 Rose has BPD (Borderline Personality Disorder) and has a "Personality" named, Marie. The "personality" Rose, displays no emotion while she talks, such as if someone were to be talking to her she would display no happiness or sadness in her speech.

 On the other hand, while talking to Dr. Jeremy Ryans, she tends to show a little emotion towards him. 

So when the line is directed to Jeremy, the character needs to show more emotion then with other people.