Joseph Nuncreed is a major character in Beacon Pines. A pharmacist and the owner of Beacon Pines's local drugstore (named "Nuncreed's Drugstore"), he was a friend of Walter VanHorn and spends a lot of the game infatuated with Luka's grandmother.

Nuncreed is a man haunted by his past and present actions, and yet struggles to find the strength needed to disobey orders from Sharper even when he knows what he's doing is reprehensible. His primary motive through most of the game's branches is to get his business with Sharper finished as soon as possible while also attempting to avoid doing harm to others, as he ultimately wants to help those around him, though he is willing to dirty his hands if anyone interferes with what he thinks "needs doing" (the man does show remorse for the things he does, however). Despite his fear towards the Founder, he often speaks critically of him as well as Perennial Harvest when they aren't present, and can be vocally frustrated when The Clipboards badger him for something.