Sayori is initially portrayed as the character archetype of a Genki Girl, expressing a bubbly and cheery disposition. She is very clumsy and noted for finding ways to accidentally hurt herself or to drop random things. Regardless, she is shown to be a jokingly cunning individual who can trick others into getting food, as shown after managing to eat Natsuki's cookie without her permission. Sayori has also been known by the protagonist to obsess over activities that she loses interest in later. She states that writing poetry and studying literature is different to her than those other interests because it helps her explore her feelings. She is Sam's best friend who accidentally moved into her neighbourhood instead of Mahiro's and both of them became neighbours. What he doesn't know is that she secretly has a crush on him, despite Sam being a transfer student for the school year. At home, she wears a pink shirt with rolled-up long sleeves and blue shorts. On the morning of her death, she is seen wearing a brown collared white dress shirt, which has a pocket on each side, brown folds and six black buttons, the top one being unbuttoned, slim-fitting red shorts and sneakers.

Her voice should be medium-high and you're free to use whatever you think this character should sound.