Voiced by Greg Chun

Ephraim is engaged in guerrilla war against Grado in an attempt to divert Grado troops from their invasion into Renais, concurrently with his father's death. Blaming himself for his inability to aid his father in his time of need, Ephraim journeys back towards his homeland in hopes of finding his sister, Eirika, who has now disappeared in the wake of the invasion. He also wants to find Prince Lyon to unravel the mystery of Grado's sudden invasion. Ephraim is passionate and headstrong, and well-liked for his candid, direct manner.

After Jehanna's Sacred Stone is destroyed, Eirika joins him to go to Renais castle to save their country and its Sacred Stone. Orson, the traitor, is in charge of Renais castle. After they take it back, it is revealed that Lyon had raised Orson's wife back from the dead, and he was happy, if consumed by madness. Ephraim then receives the Sacred Stone along with Siegmund, and Eirika receives Sieglinde. Ephraim, along with Eirika and company, ultimately defeats the Demon King, afterwards he became King of Renais and helps to fix up Magvel.