Tsunade(綱手) is one of Konohagakure's Sannin. Though celebrated as the world's strongest kunoichiand its greatest medical-nin, the repeated loss of her loved ones caused Tsunade to abandon the life of a shinobi for many years. She is eventually persuaded to return to Konoha as its Fifth Hokage(五代目火影,Godaime Hokage,Literally meaning:Fifth Fire Shadow), where her skills prove invaluable to the village.