Rosé first appears in Chapter 1 of the manga, where she greets the Elric brothers upon their fresh arrival in Reole. After the death of her boyfriend in an accident, Rosé became enamored with Father Cornello's claims that the sun god Leto was capable of answering any prayer - even the resurrection of the dead - if said prayer were made by someone devout enough and became one of the priest's foremost believers. She, at first, scoffs at Edward's staunch disbelief in resurrection and a higher power, but after the Elrics help her confront Cornello and reveal that his "miracles" were the work of alchemy and his "great cause" a selfish pursuit of military power, she collapses spiritually. As Ed and Al leave the town, she demands angrily why they had to come and destroy the only hope she had left of reuniting with her lost love, to which Edward replies that she should stand on her own power and walk forward into a future she decides for herself.