Depressed Spleen is, of course, a spleen. The rest of his body consists of a stalk made of veins and arteries. He is one of the more reproachable characters, due to his disdain of others and depressing attitude, best described as "a jaded, bitter, pessimistic, misanthropic, melodramatic, possibly masochistic glutton for misery and gloom." He also constantly complains, being an annoyance to others. He considers those that subject to his ramblings as self punishing and masochistic. He came to the Hospital to seek attention, not necessarily for treatment. Even if he doesn't have a real problem, he refuses to leave. Dr Phage recommended ignoring him until he leaves, an act he taken as far as blocking Spleen from his perception. - wiki
[A very depressed voice, but very talkative. Maybe a Snape or Marvin the depressed robot voice would fit?]